Topchiyeva Shafiga Anivarovna

Place of birth

Tbilisi, Georgia 

  

Date of birth

01.04.1951 

Education

 

Scientific degree

Doctor Biological Sciences 

Title

 

Topic of  PhD thesis:

-         specialty code

-         specialty name

-         topic name

 

15.00.02

Pharmaceutical Chemistry and Pharmacognosy

Pharmacokinetics of erinite,  isosorbide   dinitrate and isosorbide-5-mononitrate

Topic of doctoral thesis:

-         specialty code

-         specialty name

-         topic name

 

03.00.04

Biochemistry

Biochemical and pharmacokinetical characterisation  of Vipera (Vipera lebetina obtusa) 

Total number of printed scientific publications:

-          number of scientific publications printed abroad:

-          number of papers  published in journals indexed and abstracted in international databases

183

 

73

 

Number of patents and certificates of authorship

Staff training:     

-         number of  PhD

-         number of  Doctor of sciences 

 

3

Basic scientific achievements

Experience in study of pharmacokinetic and biotransformation of drugs, study of pharmacological activity and toxicity of drugs and their metabolites, clinical studies, optimization and individualization of drug therapy. Studies of drugs labelled by radioactive and stable isotopes. HPLC, TLC, GC and other analytical methods. Bioequivalence of drugs. Study of opportunities of making radiation detectors, determination of radiation activity of the radionuclides in soil, plant, water, venoms and animals. Influence of small dozes g-radiations on toxicity of venom Macrovipera lebetina obtusа and  honey bee Apis mellifere caucasica. Influence of small dozes is investigated g-radiations on toxicity and on pharmacological properties of venom Macrovipera lebetina obtusа and honey bee Apis mellifere caucasica. Electronic paramagnetic resonance in studying venom  of Macrovipera lebetina obtusa. Ecology factor and physico-chemical properties of Macrovipera lebetina obtusa’s venom. Ecological geochemical aspects of variation of the elementary ingredients of the Macrovipera lebetina obtusa’s venom. Application  an ionising radiation for sterilisation of preparations on the basis of venom of Macrovipera lebetina obtusа and venom honey bee Apis mellifere caucasica. Laser spectroscopy in the investigations on spectral-luminescent properties of snake venom and its metabolites. Laser spectroscopy method in the studing of snake venom.  The influence of the environmental factors on chemical composition of Macrovipera’s venom. Fluorescent probes in snake venom investigation. Preparation of ecological pure poison of Apis mellifera caucasica. Comprative aspects of venom of amphibies and reptilies. Study of the effect of phynoptine  on meiotic maturing of oocytes  in vitro. Study of severe toxicity of ascorbic acid. Influence of small dozes  gamma-radiations on molecular mobility, spectral characteristics and pharmacological properties of poison of honey bee –Apis mellifera caucasica. Radiation sterilization of venom of  snake and stading  its spectral characteristics. Radiating and temperature of-drying QF a ordinary barberry Berberis vulgaris L. To ecology and distribution of rale kinds of amphibious of Azerbaijan. Perspectives of microbial ferments use as the vaccine preparations. Biological control of diaspis (Homoptera) with coccinellid-Rizobius lophanthae Blaisd (Coleoptera) in Azerbaijan. Influence of electromagnetic radiation on venom of Vipera lebetina obtuse. Photodetectors on the Base of Heterocontact Semiconductor – Snake Venom. Heterocontact monoselenide indium p-type conductivity and crystal viper venom (venom-p-InSe) established and it was found that heterojunction in zootoxins behaves like a p-type semiconductor conductivity.  Impact of environmental factors (heavy metals) on biodiversity of spiders. Investigation of Electrophysical Parameters of venom of Macrovipera lebetina obtusа and  honey bee Apis mellifere caucasica. Expertise and experience in addressing other global problems of ecology, toxicology, pharmacology, biology and medicine. 

Names of scientific works

1. Topchiyeva Sh.A., Chumburidze B.I., Kaviladze M.Sh., Sepiashvili L.D. The biotransformation of erinit and investigation structure of its dominant metabolite. //Journal “Pharmakologiya I toksikologiya”, Moscow, 1986, №1, p.71-72.

2. Topchiyeva Sh.A., Fluorescent probes in snake venom investigation. Journa ”Farmakom”,Xarkov, 2002, №3, pp.174-179.

3. Topchiyeva Ş., Qəndilov R., Haciyeva A. Həyatı bacarıqlara əsaslanan təsil. Müəllimlər üçün tədris vəsaiti (V-IX siniflər), Bakı, 2006, 606 s.

4. Топчиева Ш.А., Мехрабова М.А., Абиев Г.А. и др. Активность радионуклидов в составе змеиного яда. Ж. “Альтернативная энергетика и экология”, Санкт-Петербург, 2010, № 6, с.138-144.

5. Абиев Г.А., Топчиева Ш.А., Мехрабова М.А., Бабаев Э. Т. Определение радионуклидов в составе змеиного яда. Возможности создания детекторов на их основе. Ж. Вестник МГОУ, Серия «Естественные науки»,. Москва, 2011, №3., c.7-12.

6. Abiyev Huseyn, Topchiyeva Shafiga. Macrovipera lebetina obtusa venom as a biological indicator of environmental pollution. Journal of Applied Environmental and Biological Sciences (JAEBS) (Thomson Reuters ISI indexed) It will be published on the Vol. 3, No. 10, October, 2013, p.33-40.

7. Abiyev Huseyn, Topchiyeva Shafiga. Influence of ionizing radiation on the physical and chemical properties of venom of snake Macrovipera lebetina obtusa. Journal of Basic and Applied Scientific Research(JBASR) (Thomson Reuters ISI indexed),Vol. 3, No. 10, October, 2013.p.265-269.

8. Abiyev Huseyn, Topchiyeva Shafiga. The study of the physical properties of Мacrovipera lebetina obtusа venom. Journal of Basic and Applied Scientific Research(JBASR) (Thomson Reuters ISI indexed),Vol. 3, No. 11, November, 2013.p.373-377.

Membership with international and foreign scientific organizations

  1. Prof. of  International   Ecoenergy   Academy, Baku, Azerbaijan.
  2. Academician of the International Academy of Ecology  and Life  Protection Sciences, Russia.
  3. Deputy head of the Center of Innovation and Technology Commercialization. The Chief Technology Commercialization Officer, Baku, Azerbaijan, ANAS

Pedagogical activity

1994-1995 year,  Azerbaijan Medical University,

Department of Clinical Pharmacology,

lectures on  "Molecular Pharmacology".

Other activities

Editorial Board of   journal:

  1. Scientific Journal of  Az. Medical University ”Azarbaijan Pharmaceutical  and  Pharmakoterapia”
  2. Scientific Journal of  Riga Thenical University  “SAFETI OF TECHNOGENIC ENVIRONMENT”
  3. “Nova Explore Journals”  

Awards and prizes

Certificate of  Honor  ANAS

Main place of work and its address

Institute of Zoology, National Academy of Sciences of Azerbaijan

AZ1073,  Baku, Azerbaijan, Pass.1128, block 504

Position

 

Office phone

 

Mobile

(+994 50) 6324912 

Home phone

(+99412) 4322875 

Fax

 

E-mail

shafiga.topchiyeva@mail.ru